Staff
 
 
 
   

Mikhail Kleshnin
Junior research scientist of the Department for radiophysics methods in medicine

Education:
2001 – 2007: Student at the radiophysics faculty, Nizhny Novgorod State University
2005: BC degree, Radiophysics
2005: MS degree, Radiophysics
2007 – 2010: postgraduate student at the IAP RAS

Scope of professional interests:

  • Development of optical devices for biomedical diagnostics
  • Small animal fluorescence imaging
  • Diffuse optical tomography
  • Image analysis and processing
  • Automated control systems

Professional career:
2007 - present: Junior research scientist at the IAP RAS

Membership in professional organizations:
2008 – present: member of the International Society for Optical Engineering (SPIE).

Awards, prizes, grants:
2013 – Silver medal for invention "Diffuse fluorescence tomography setup for biomedical research", 24-th International Invention, Innovation & Technology Exibition ITEX 2013, Malaysia, Kuala Lumpur, 9-11 May 2013 (authors: Turchin Ilya, Kleshnin Mikhail, Kamensky Vladislav, Fiks Ilya)
2011 – Gold medal of the Kulibin inventor (Optical diffuse tomography setup)
2008 – Scholarship of the Razuvaev academician
2007 – Scholarship of the Razuvaev academician
2012-2013: grant of the Russian Foundation for Basic Research «Spectrally-resolved diffuse fluorescent tomography»

Publications:
11 peer-reviewed journal publications, 1 book chapters, 24 conference proceedings, 12 conference abstracts, 4 patents

  1. A.P. Savitsky, I.G. Meerovich, V.V. Zherdeva, L.R. Arslanbaeva, O.S. Burova, D.V. Sokolova, E.M. Treshchalina, A.Yu. Baryshnikov, I.I. Fiks, A.G. Orlova, M.S. Kleshnin, I.V. Turchin, A.M. Sergeev. Three-dimensional in vivo imaging of tumors expressing red fluorescent proteins // R.M. Hoffman (ed.) In vivo cellular imaging using fluorescent proteins: Methods and protocols, (NJ. Humana Press. – 269 p.) p.97-114, 2012.
  2. I.V. Turchin, V.I. Plehanov, A.G. Orlova, V.A. Kamensky, M.S. Kleshnin, M.V. Shirmanova, N.M. Shakhova, I.V. Balalaeva, A.P. Savitsky. Fluorescence diffuse tomography of small animals with DsRed2 fluorescent protein // Las. Phys., 16(5), p.741-746, 2006.
  3. I.V. Turchin, I.V. Balalaeva, R.B. Vasil’ev, V.P. Zlomanov, V.I. Plehanov, A.G. Orlova, E.V. Zagaynova, V.A. Kamensky, M.S. Kleshnin, M.V. Shirmanova, S.G. Dorofeev, D.N. Dirin. Imaging of QDs-labeled tumors in small animals by fluorescence diffuse tomography // Las. Phys. Let., 3(4), p.208-211, 2006.
  4. A.G. Orlova, I.V. Turchin, V.I. Plehanov, N.M. Shakhova, I.I. Fiks, M.S. Kleshnin, N.Yu. Konuchenko, V.A. Kamensky. Frequency-domain diffuse optical tomography with single source-detector pair for breast cancer detection // Las. Phys. Let., 5(4), p.321-327, 2008.
  5. I.V. Turchin, V.A. Kamensky, V.I. Plehanov, A.G. Orlova, M.S. Kleshnin, I.I. Fiks, M.V. Shirmanova, I.G. Meerovich, L.R. Arslanbaeva, V.V. Jerdeva, A.P. Savitsky. Fluorescence diffuse tomography for detection of red fluorescent protein expressed tumors in small animals // J. Biomed. Opt., 13(4), p.041310-10, 2008.
  6. M.S. Kleshnin, I.V. Turchin. Spectrally-resolved diffuse fluorescent tomography // Quantum electron., 40(6), p.531-537, 2010.
  7. M.V. Shirmanova, E.V. Zagaynova, M.A. Sirotkina, L.B. Snopova, I.V. Balalaeva, I.V. Krutova, N.Yu. Lekanova, I.V. Turchin, A.G. Orlova, M.S. Kleshnin. In vivo study of photosensitizers pharmacokinetics by fluorescence transillumination imaging // J. Biomed. Opt., 15(4), p.0480041-8, 2010.
  8. M.S. Kleshnin, I.V. Turchin. Fluorescence diffuse tomography technique with autofluorescence removal based on dispersion of biotissue optical properties // Las. Phys. Lett., 10(7), p.075601/1-6, 2013.
  9. I.I Fiks, M.Yu. Kirillin, E.A. Sergeeva, M.S. Kleshnin, I.V. Turchin. Reconstruction of fluorophore distribution for fluorescence diffuse tomography based on hybrid model // SPIE Proc., v. 7369, 2009.
  10. M.S. Kleshnin, I.I. Fiks, I.V. Turchin, I.V. Balalaeva, A.P. Savitsky. Small animal fluorescence imaging with lifetime and spectral resolution for detection of RFP-expressed tumors // Proc. of International Symposium «Topical problems of biophotonics - 2011», 2011.
  11. M.S. Kleshnin, I.I. Fiks, A.G. Orlova, I.V. Balalaeva, M.V. Shirmanova, I.V. Turchin, «Versatile system for small animal fluorescence imaging», Proc. of International Symposium «Topical problems of biophotonics - 2013», 2013.
  12. И.В. Турчин, В.А. Каменский, В.И. Плеханов, А.Г. Орлова, М.С. Клешнин. Устройство получения флуоресцентных томографических изображений // Патент на изобретение № 2368306, 2009.
  13. М.В. Ширманова, Е.В. Загайнова, И.В. Балалаева, М.А. Сироткина, И.В. Турчин, М.С. Клешнин. Способ прижизненного исследования фотосенсибилизаторов // Патент на изобретение № 2373973, 2009.
  14. В.А. Каменский, И.В. Турчин, А.Г. Орлова, М.С. Клешнин, В.И. Плеханов. Устройство диффузионной оптической томографии // Патент на полезную модель № 91517, 2010
  15. В.А. Каменский, И.В. Турчин, М.С. Клешнин, И.И. Фикс. Устройство диффузионной флуоресцентной томографии // Патент на изобретение № 2441582, 2012.